Hôpital Sainte Croix is located in Leogane, twenty miles west of Port-au-Prince. Started as a small aid station by a Haitian Episcopal priest in the late 60s it now fills a five-acre urban compound. The hospital has grown to a 120-bed institution, offering comprehensive in-patient and out-patient services for the poor. Facilities include four operating theaters, two delivery rooms, a dental clinic, laboratory services and a 24-hr. emergency room. A midwifery education program trains and supervises midwives to serve in the rural area surrounding Leogane . An extensive community health program provides backup support to over 100 village health workers whom the hospital has trained and who work in thirteen clinics, some of which are accessible only by walking.

Health conditions in Leogane, a city of over 100,000 people, mirror the poverty and disease that afflicts all of Haiti, the poorest country in the Western hemisphere. Life expectancy is only 42 years. Inadequate nutrition and poor sanitation contribute to illness, malnutrition, and skin diseases. Respiratory infections are common in children, and infant mortality rates are extremely high. Among adults, HIV/AIDS continues to be a critical health issue and malaria is a chronic health problem in the outlying areas. Hopital Sainte Croix conducts Lymphatic Filariasis ("Elephantiasis") screening and treatment clinics in four outlying communities. The hospital also operates a community medical training center at Darbonne, where more than 900 health workers have been trained since 1982.

The hospital carries out its mission in a facility that lacks adequate surgical and laboratory equipment and struggles daily with failing electrical and plumbing systems. Presbyterians from many U.S. congregations regularly provide both medical mission teams to the Leogane area and assistance with repairs and maintenance to the hospital facilities, but the forces of a weakening national economy and political instability have compounded the challenges facing the hospital's staff and it's dedicated supporters in the U.S.